Big Picture Science
Big Picture Science
Make Space for Animals
SummaryIn this episode of Big Picture Science, hosts Seth Shostak and Molly Bentley explore humanity’s complex and often fraught relationship with the animal kingdom. The discussion begins with zoologist Joe Wimpenny, author of Aesop’s Animals: The Science Behind the Fables. Wimpenny examines how ancient fables have shaped our perception of animal behavior for millennia, often through anthropomorphism. While some stories, such as the crow using stones to raise water levels, show surprising scientific accuracy, others like the wolf in sheep’s clothing mischaracterize animal intelligence and perpetuate harmful biases. The hosts reflect on whether these age-old narratives influence how we treat animals today, especially in the context of biodiversity loss. The episode further shifts to a bittersweet look at the history of animals in space. Graphic editors Taylor Magakimo and Alexander Stegmeier discuss their work documenting the various species—from dogs and primates to microscopic tardigrades—that served as involuntary pioneers during the space race. The conversation highlights the ethical complexities of these missions, the individual identities of the animals involved, and the scientific insights gained that paved the way for human space exploration.
Updated Jun 22, 2026
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CRISPR Mosquitoes
SummaryThis episode of Big Picture Science explores the revolutionary potential and complex ethical landscape of CRISPR and gene-editing technologies. The hosts investigate how scientists are currently utilizing genetic tools to address public health crises, specifically focusing on the control of disease-carrying mosquitoes. Through an interview with Dr. Nathan Rose of Oxitec, the discussion highlights how gene-limiting technology—which differs from CRISPR—is being used to reduce populations of invasive mosquitoes that transmit Zika, dengue, and malaria, providing a targeted alternative to chemical insecticides. Beyond the practical applications in pest control, the episode delves into the broader implications of CRISPR in human medicine. Law professor Hank Greely provides expert insight into the distinction between somatic and germ-line editing, emphasizing the rapid, accessible nature of CRISPR compared to previous methods. The conversation examines the immense promise of gene therapy for treating genetic conditions like sickle cell anemia, while simultaneously addressing the ethical dangers of human embryo editing. By balancing the excitement of medical breakthroughs with the necessity for rigorous safety and ethical oversight, the episode offers a comprehensive look at how we are rewriting the biological code.
Skeptic Check: Blue Light Special
SummaryThe hosts of Big Picture Science investigate the pervasive belief that blue light emitted from modern electronic devices is the primary culprit behind the global rise in insomnia. While conventional wisdom suggests that the glow from phones and tablets suppresses melatonin and keeps users awake, the episode presents a compelling challenge to this narrative. Sleep researcher Dr. Michael Gradizar shares his findings, which demonstrate that the light intensity from typical screens is significantly lower than what is required to alter human circadian rhythms. He argues that the actual lux levels produced by devices are surprisingly minimal, suggesting that the popular link between blue light and sleep disruption is largely unsupported by rigorous evidence. Beyond the screen-time debate, the episode explores the broader biology of circadian rhythms with geneticist Dr. J. Dunlap. The discussion delves into how these internal biological clocks function as self-sustained molecular oscillators, present in almost every cell, and how they are synchronized by environmental "time-givers" like light and temperature. Ultimately, the program highlights a fascinating disconnect between scientific data and public perception, urging listeners to look beyond the "blue light" myth to better understand the true drivers of sleep quality.
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