ON

On with Kara Swisher

Vox Media

Is It Possible to Hack Your Body for a Longer Life?

May 23, 20261h 4m
Summary

In this episode, Kara Swisher explores the complex and often controversial world of longevity research, shifting away from the sensationalism surrounding tech billionaires toward a more data-driven approach to health. She sits down with oncologist and researcher Dr. David Agus to discuss the intersection of cutting-edge technology and patient care. Dr. Agus, who played a pivotal role in Swisher’s own medical journey by identifying and treating a serious heart condition, emphasizes that true longevity isn't about magical serums or fringe biohacking. Instead, he advocates for a rigorous, evidence-based lifestyle. The discussion covers the critical role of AI in accelerating drug discovery and clinical efficiency, while also highlighting the urgent need for a national strategic plan for healthcare. Dr. Agus warns against the "experiment of one" mentality often seen on social media, noting that without robust data, these individual health interventions can be both ineffective and dangerous. The conversation reinforces the importance of foundational habits—such as consistent sleep, regular eating schedules, and social connectivity—over expensive, unproven trends, ultimately framing health as a long-term commitment to evidence-based, preventive medicine.

Updated May 23, 2026

About This Episode

From GLP-1’s to peptides to hyperbaric chambers, we’re awash in medical information and wellness trends. But what do we really know about improving longevity and increasing your healthspan?  This is the first episode of the Hacking Longevity series. Kara breaks down the best advice for actually living longer (spoiler alert: it’s boring, and you probably already know it), and hears from some members of her own medical team about how to make the best health decisions.  First is Dr. David Agus, the founding CEO of the Ellison Medical Institute. Later on, she leads a roundtable discussion with  Dr. Ezekiel “Zeke” Emanuel, an oncologist, public health expert and author of Eat Your Ice Cream: Six Simple Rules for a Long and Healthy Life. Plus two members of her own personal care team: Dr. David Daniels, a cardiologist at Sutter Health in San Francisco and the founder of Solo Pace. (He’s also the surgeon who repaired the heart defect that led to Kara’s 2011 stroke.) And Jason Braun, founder of the Tidal Elite Performance Center in Washington and Kara’s own personal trainer. Questions? Comments? Email us at on@voxmedia.com or find us on YouTube, Instagram, TikTok, Threads, and Bluesky @onwithkaraswisher. Learn more about your ad choices. Visit podcastchoices.com/adchoices

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